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The Case for LESS Sensitive COVID Tests

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Channel: minutephysics
Categories: Biology   |   Health   |   Science  
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This video written & produced in collaboration with Aatish Bhatia,

This video is about how cheap, fast, and LESS sensitive rapid antigen tests might be better for screening (& maybe surveillance) than PCR COVID tests due to the nature of contagiousness/infectiveness at various points on the viral load trajectory of symptomatic and asymptomatic COVID sars-COV-2 carriers.


Thanks to Daniel Larremore for feedback on early versions of this video

Rapid Antigen Testing:

COVID-19 testing: One size does not fit all.

Rethinking Covid-19 Test Sensitivity A Strategy for Containment.

Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening.

The effectiveness of population-wide, rapid antigen test based screening in reducing SARS-CoV-2 infection prevalence in Slovakia. (pre-print, not yet peer reviewed)

Effective Testing and Screening for Covid-19.

Brown University & Harvard University modeling of COVID-19 testing shortfall.

Fast Coronavirus Tests are coming.

Open letter signed by epidemiologists and infectious disease experts supporting widespread & frequent rapid antigen testing for COVID-19:

More information on various COVID-19 tests:

Field performance and public health response using the BinaxNOW Rapid SARS-CoV-2 antigen detection assay during community-based testing.

Performance of an Antigen-Based Test for Asymptomatic and Symptomatic SARS-CoV-2 Testing at Two University Campuses.

Asymptomatic Spread:

People without symptoms spread virus in more than half of cases, CDC model finds

(More than half of all) SARS-CoV-2 Transmission From People Without COVID-19 Symptoms.

Three Quarters of People with SARS-CoV-2 Infection are Asymptomatic: Analysis of English Household Survey Data.

Viral Load Curve:

SARS-CoV-2 viral dynamics in acute infections. (pre-print, not yet peer reviewed)

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Created by Henry Reich

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