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Why Are Antibody Tests Failing?

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 Biology   |   Chemistry   |   Health   |   Science
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Description

Many people are wondering if that bad cold they had back in February or March was actually the new coronavirus. In principle, an antibody test could tell you that, but most of the tests out there right now arent very good. We chatted with David Kroll to learn how these tests work, where they go wrong and why a test thats 96% accurate is actually pretty bad. #coronavirus #immune. #antibodytest

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Credits:
Executive Producers:
George Zaidan
Hilary Hudson

Producers:
Andrew Sobey
Elaine Seward

Writer/Host:
Samantha Jones, PhD

Scientific consultants:
David Kroll, PhD
Brianne Raccor, PhD
Michelle Boucher, PhD

Special Thanks:
Ruben Rodriguez

Sources:
Insight into FDAs Revised Policy on Antibody Tests: Prioritizing Access and Accuracy
https://www.fda.gov/news-events/fda-voices/insight-fdas-revised-policy-antibody-tests-prioritizing-access-and-accuracy?utm_campaign=Insight%20into%20FDA%E2%80%99s%20Revised%20Policy%20on%20Antibody%20Tests%3A%20Prioritizing%20Access%20and%20Accuracy&utm_medium=email&utm_source=Eloqua

EUA Authorized Serology Test Performance
https://www.fda.gov/medical-devices/emergency-situations-medical-devices/eua-authorized-serology-test-performance

CDC: Serology Testing for COVID-19
https://www.cdc.gov/coronavirus/2019-ncov/lab/serology-testing.html

Coronavirus: surprisingly big problems caused by small errors in testing
https://theconversation.com/coronavirus-surprisingly-big-problems-caused-by-small-errors-in-testing-136700

Antibody Test, Seen as Key to Reopening Country, Does Not Yet Deliver
https://www.nytimes.com/2020/04/19/us/coronavirus-antibody-tests.html

Prominent scientists have bad news for the White House about coronavirus antibody tests
https://www.cnn.com/2020/04/14/health/coronavirus-antibody-tests-scientists/index.html

The FDA Said It Will Now Crack Down On Shoddy Coronavirus Antibody Tests
https://www.buzzfeednews.com/article/stephaniemlee/coronavirus-fda-antibody-tests-accuracy

F.D.A. Approves First Coronavirus Antibody Test in U.S.
https://www.nytimes.com/2020/04/02/health/coronavirus-antibody-test.html

Why We Need Antibody Testing, and Fast
https://www.nytimes.com/2020/04/13/opinion/coronavirus-antibodies-test.html

Coronavirus: How to tell if your misery was really COVID-19
https://www.mercurynews.com/2020/04/12/coronavirus-how-to-tell-if-your-misery-was-really-covid-19/

Michigan hospital system will test workers blood in effort to help reopen country
https://www.washingtonpost.com/health/michigan-hospital-system-will-test-workers-blood-in-effort-to-help-reopen-country/2020/04/13/20830d1e-7ccd-11ea-a3ee-13e1ae0a3571_story.html

Test for antibodies against novel coronavirus developed at Stanford Medicine
http://med.stanford.edu/news/all-news/2020/04/stanford-medicine-develops-antibody-test-for-coronavirus.html

Fears of Wild West as COVID-19 blood tests hit the market
https://www.sltrib.com/news/2020/04/12/fears-wild-west-covid/

Will an Antibody Test Allow Us to Go Back to School or Work?
https://www.nytimes.com/2020/04/10/health/coronavirus-antibody-test.html

The UK has ordered millions of coronavirus antibody tests which don't work and functional ones could be months away
https://www.businessinsider.com/coronavirus-scientists-warn-that-antibody-tests-could-be-months-away-2020-4

FDA approves first antibody test in the US to detect the coronavirus
https://www.livescience.com/first-coronavirus-antibody-test-approved-us.html

'No Evidence' Yet That Recovered COVID-19 Patients Are Immune, WHO Says
https://www.npr.org/sections/coronavirus-live-updates/2020/04/25/844939777/no-evidence-that-recovered-covid-19-patients-are-immune-who-says

Rapid COVID-19 Antibody Detection Tests: Principles and Methods
https://www.assaygenie.com/rapid-covid19-antibody-detection-tests-principles-and-methods


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