Can we live forever? Human skin cells REVERSED in age!

Scientists in the UK have reversed the age of skin cells using Maturation Phase Transient Reprogramming to reverse the skin cells of a 58 year old man by 30 years. His skin markers were compared to someone of 30 years his junior and not only did his skin reverse in age, but so did many other properties of the skin cells.

The Alzheimer's gene was also shown to be impacted in a postive way, collagen was given a "youthful" impact. Although this trial was in Vivo, it will lead the way into human trials into Juvenescence.

I explain the basics around stem cells, IPSC (Pluripotent stem cells) and MPTR. I also simply all of these points.

Timecodes
0:00 - Intro Skin cells reversed
0:14 - Paper on ELifeSciences
0:24 - Someone will live to 250
0:44 - What are stem cells
1:34 - Yamanaka Factors
2:10 - Maturation Phase Transient Reprogramming
3:55 - Collagen levels increased
4:27 - Alzheimer's down regulation
4:44 - Skin wound healing
5:00 - Parabiosis - reverse age of organs
5:27 - eLifeSciences Paper transcription age
6:03 - Telomeres
6:44 - Not in vivo
6:55 - Diljeet, Wolf, Twitter

https://www.ucsf.edu/news/2007/11/102476/shinya-yamanaka-reprograms-human-adult-cells-embryonic-stem-cells#:~:text=Shinya%20Yamanaka%20Reprograms%20Human%20Adult%20Cells%20into%20Embryonic%2Dlike%20Stem%20Cells,-By%20Valerie%20Tucker&text=By%20Valerie%20Tucker%20Acclaimed%20stem,embryonic%20stem%20(ES)%20cells.

https://en.wikipedia.org/wiki/Induced_pluripotent_stem_cell
https://elifesciences.org/articles/71624#sa2exam
https://www.babraham.ac.uk/our-research/epigenetics/wolf-reik