What Happens to the Human Body in Space?
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In the largest study of its kind, scientists are coming closer to understanding exactly how space affects the human body.
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Back in 2019, NASA published the first ever space twin study. This compared twins Mark and Scott Kelly before, during, and after Scott spent 340 days in spacethats the longest any U.S. astronaut has consecutively spent in spaceflightwhile Mark stayed here on Earth. That study gave us so much insight into how the human body changes in microgravity: from telomere shortening to gut microbiome changes to rapid alteration of gene expression. It also told us there was still so much to learn...and 2020 delivered.
A set of nineteen new studies builds on the results of the Kelly Twins study, reanalyzing some of that data and comparing those results to measurements between 56 astronauts in total. Plus ten more papers are in pre-print now, being reviewed and set for publication soon to add even more to this data set. This is the largest study of its kind, the most information EVER collected about what happens to the human body in space.
The researchers have identified, for the first time, a core set of mammalian adaptations in response to spaceflight. We see these changes across species: humans, mice and other animals. The biggest one? Mitochondrial dysfunction. You may think of the mitochondria as that famous powerhouse of the cellit generates most of the energy a cell needs and so enables the proper function of all your tissues and organs. And as you might imagine, keeping your mitochondria working is pretty important. Using new techniques that allowed a really in-depth look at changes in the astronauts genomes and protein expression, mitochondrial changes were consistent across the dataset. And even though the scientists are still unsure what EXACTLY may be the underlying cause of this mitochondrial disturbance, they think its likely oxidative stress caused by the extreme environment of space. This, essentially, is damage caused to cells by stress. Stress releases these harmful compounds called reactive oxygen species, causing genetic changes that, in turn, cause changes in metabolic pathways.
#NASA #astronauts #MarkKelly #ScottKelly #science #seeker #elements
Read More:
Space travel can seriously change your brain
https://www.space.com/brain-changes-in-space-astronaut-health-study.html
"Since the days of the shuttle program to today, astronauts have reported issues with vision after traveling to space. Medical evaluations on Earth have revealed that astronauts' optic nerves swell and some experience retinal hemorrhage and other structural changes to their eyes."
What happens to an astronaut's body in space
https://www.businessinsider.com/space-antigravity-radiation-affect-human-body-2019-9
"The immune system also takes a hit. Researchers discovered that a lack of gravity weakens the functions of T cells, which play a crucial role in fighting off diseases."
Spaceflight does some weird things to astronauts bodies
https://www.technologyreview.com/2020/11/25/1012628/spaceflight-astronauts-bodies-genetics-effects-scott-kelly-twins-study/
"he Kelly twins offered scientists a rare opportunity: as they studied what happened to Scotts body during his year in space, they had the benefit of a control subject, Mark, who stayed on Earth."
____________________
Elements is more than just a science show. Its your science-loving best friend, tasked with keeping you updated and interested on all the compelling, innovative and groundbreaking science happening all around us. Join our passionate hosts as they help break down and present fascinating science, from quarks to quantum theory and beyond.
Seeker empowers the curious to understand the science shaping our world. We tell award-winning stories about the natural forces and groundbreaking innovations that impact our lives, our planet, and our universe.
Visit the Seeker website https://www.seeker.com/videos
Elements on Facebook https://www.facebook.com/SeekerElements/
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Seeker on Twitter http://twitter.com/seeker
Seeker on Facebook https://www.facebook.com/SeekerMedia/
Seeker http://www.seeker.com/
Subscribe to Seeker! http://bit.ly/subscribeseeker
Watch more Elements! http://bit.ly/ElementsPlaylist
Visit our shop at http://shop.seeker.com
Back in 2019, NASA published the first ever space twin study. This compared twins Mark and Scott Kelly before, during, and after Scott spent 340 days in spacethats the longest any U.S. astronaut has consecutively spent in spaceflightwhile Mark stayed here on Earth. That study gave us so much insight into how the human body changes in microgravity: from telomere shortening to gut microbiome changes to rapid alteration of gene expression. It also told us there was still so much to learn...and 2020 delivered.
A set of nineteen new studies builds on the results of the Kelly Twins study, reanalyzing some of that data and comparing those results to measurements between 56 astronauts in total. Plus ten more papers are in pre-print now, being reviewed and set for publication soon to add even more to this data set. This is the largest study of its kind, the most information EVER collected about what happens to the human body in space.
The researchers have identified, for the first time, a core set of mammalian adaptations in response to spaceflight. We see these changes across species: humans, mice and other animals. The biggest one? Mitochondrial dysfunction. You may think of the mitochondria as that famous powerhouse of the cellit generates most of the energy a cell needs and so enables the proper function of all your tissues and organs. And as you might imagine, keeping your mitochondria working is pretty important. Using new techniques that allowed a really in-depth look at changes in the astronauts genomes and protein expression, mitochondrial changes were consistent across the dataset. And even though the scientists are still unsure what EXACTLY may be the underlying cause of this mitochondrial disturbance, they think its likely oxidative stress caused by the extreme environment of space. This, essentially, is damage caused to cells by stress. Stress releases these harmful compounds called reactive oxygen species, causing genetic changes that, in turn, cause changes in metabolic pathways.
#NASA #astronauts #MarkKelly #ScottKelly #science #seeker #elements
Read More:
Space travel can seriously change your brain
https://www.space.com/brain-changes-in-space-astronaut-health-study.html
"Since the days of the shuttle program to today, astronauts have reported issues with vision after traveling to space. Medical evaluations on Earth have revealed that astronauts' optic nerves swell and some experience retinal hemorrhage and other structural changes to their eyes."
What happens to an astronaut's body in space
https://www.businessinsider.com/space-antigravity-radiation-affect-human-body-2019-9
"The immune system also takes a hit. Researchers discovered that a lack of gravity weakens the functions of T cells, which play a crucial role in fighting off diseases."
Spaceflight does some weird things to astronauts bodies
https://www.technologyreview.com/2020/11/25/1012628/spaceflight-astronauts-bodies-genetics-effects-scott-kelly-twins-study/
"he Kelly twins offered scientists a rare opportunity: as they studied what happened to Scotts body during his year in space, they had the benefit of a control subject, Mark, who stayed on Earth."
____________________
Elements is more than just a science show. Its your science-loving best friend, tasked with keeping you updated and interested on all the compelling, innovative and groundbreaking science happening all around us. Join our passionate hosts as they help break down and present fascinating science, from quarks to quantum theory and beyond.
Seeker empowers the curious to understand the science shaping our world. We tell award-winning stories about the natural forces and groundbreaking innovations that impact our lives, our planet, and our universe.
Visit the Seeker website https://www.seeker.com/videos
Elements on Facebook https://www.facebook.com/SeekerElements/
Subscribe now! http://www.youtube.com/subscription_center?add_user=dnewschannel
Seeker on Twitter http://twitter.com/seeker
Seeker on Facebook https://www.facebook.com/SeekerMedia/
Seeker http://www.seeker.com/
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