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You Are Always Mutating

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Channel: But Why?
Categories: Biology   |   Health   |   Science  
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Description

Cancer is a spooky demon. It's the inevitable accumulation of mutations within our genome yet... why does it happen at all?

Big thanks to William Norberg for making the custom intro, thumbnail, and some assets for me! Check out his art here: https://www.instagram.com/blenderfoto/

Acknowledgements:
-Brady Johnson's method for DNA model - https://youtu.be/m7bTEABoAzo

-CVallance Cell model I used - https://skfb.ly/JnBC




Sources/Further Reading:

Carcinogens and DNA damage - https://dx.doi.org/10.1042%2FBST20180519

TP53: a key gene in human cancer - https://doi.org/10.1016/S0300-9084(01)01356-6

Somatic Mutations - https://doi.org/10.13070/mm.en.8.2673

Tumor-Suppressor Functions of the TP53 Pathway - https://dx.doi.org/10.1101%2Fcshperspect.a026062

DNA Replication and Causes of Mutation - https://www.nature.com/scitable/topicpage/dna-replication-and-causes-of-mutation-409/

Human Chromosome Translocations and Cancer - https://www.nature.com/scitable/topicpage/human-chromosome-translocations-and-cancer-23487/ -

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